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Administration of Multiple IM Doses of RhIG


Clarest

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Hi all,

In the chapter 22 of 17th and 18th editions of AABB Technical Manuals, it states that "Multiple IM (intramuscular) doses should be given at different sites or at different times within 72 hours". I am wondering how to define the "multiple", more than one or 5 doses. The reason I mention "5" here is that in my previous and current working places, they either says "No more than 5 doses of RhIG should be injected intramuscularly at one time" or "If more than 5 vials of RhIG are required, they should be spaced out over 72 hours." I tried to find the base of these statement from the product inserts or monograph, but not successful. Could anybody share some information on this? Thank you.

Clarest

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