AHG crossmatch for "rhogam" antibody?

[mollyredone]

Currently our policy is to perform a gel crossmatch on any patient with a history of an antibody, whether the screen is positive or negative.  I was wondering what other hospitals do when the antibody is residual Rhogam, with a date of injection given.  Do you perform an extended crossmatch?  Or do you just give Rh negative units?

 

Thanks, Mari

[Dansket]

If the current antibody screen is negative, patients with a history of anti-D due to Rh Immune Globulin injection qualify for electronic crossmatch in our computer system.  We use the term "RhIG" to designate passively-acquired anti-D that is configured as "not clinically significant".

[AuntiS]

We just give Rh Neg units here if the antibody is from only RhIG.  No IAT XM required.

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[Sandy L]

We would do an extended Gel XM as long as the current screen is positive.  It's required by the LIS.  The computer system disqualifies them for electronic XM in this instance.  If the screen becomes negative in the future, they would qualify for electronic XM as the antibody is classified as not clinically significant

[John C. Staley]

I really like the way Dansket and Sandy L. have it set up.  It is very similar to how we planned to do it once we had electronic crossmatching in place at my last transfusion service. 

[Auntie-D]

We fully XM as our 'abbreviated D-screen' doesn't exclude anti-Cw and that other pesky one which I forget right now.

 

In theory we can assign antigens to the units, select antigen neg units and EI but management are twitchy about that idea...

[BankerGirl]

If the current antibody screen is negative, patients with a history of anti-D due to Rh Immune Globulin injection qualify for electronic crossmatch in our computer system.  We use the term "RhIG" to designate passively-acquired anti-D that is configured as "not clinically significant".

We do exactly the same here and document the date of injection.  When the current screen is positive, the LIS won't allow electronic crossmatch, but all that is required is an immediate spin, not AHG, since it is not clinically significant.

[Dansket]

We do all our testing on ProVue.  I have standardized this process so that whenever crossmatching is done on ProVue, users are required to do both Buffered Gel crossmatch and Anti-IgG Gel crossmatch for patients with a positive antibody screen, regardless of patient history.  We are a small facility.

[David Saikin]

When I had a BBIS I had RhIg anti-D set up as a clinically not significant antibody so the ahgxm was not required.

[Byfaith]

We do the same as Banker Girl - Electronic XM if current screen is negative;  IS if current screen is positive due to passive Anti-D (not clinically significant in our system)