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Granulocyte


B Postive

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Cartainly, way back, when I was working in hospitals (and Noah was building his Ark), we always used to cross-match these because, as David says, they contained a lot of red cells. Given that these tend only to be transfused in extremis, when the patient is already very ill, the last thing they would want is a transfusion reaction to add to their woes.

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I agree with David & Malcolm.

 

We had a clinical trial going on with end stage ca patients with multiple mets. They were to be transfused with granulocyte concentrates (GCs) according to the trial protocol, but cross matching of GCs was not included in it.

 

When the actual unit was sent for transfusion, the ICU doctors saw the GCs contained a lot of red cells. So they referred the blood bank and we went & saw the guidelines for GC on net and recommended cross-matching. The same was incorporated in the protocol.

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