Jump to content

Protamine Sulphate? FDP?


froggymork

Recommended Posts

  • 1 month later...

Why or perhaps How did the protamine sulfate test fall out of favor? I looked through several coagulation sections of hematology textbooks and there is no to minimal references to this test (which should tell me something right there!). What is a good suggestion to replace or substitute for this test?

Our laboratory is looking at revising our coagulation testing. This is one test on our revision list but we have a pathologist who is reluctant to give it up. What can I offer him in exchange for this?

Link to comment
Share on other sites

Protamine sulfate is used for other purposes in medicine, but if I am not mistaken, its main use in Lab testing is to differentiate DIC (and other simular thrombotic problems like pulmonary embolism and deep vein thrombosis) from primary fibrinolysis. It seems to me that the D-dimer, which is specific for cross-linked fibrin, has made this test obselete.

Quantitative D-dimer assays can be easily run on most automated coagulation analyzers. There are also point-of-care analyzers that will run d-dimers.

Scott

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Recently Browsing   0 members

    • No registered users viewing this page.
  • Advertisement

×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.