who can make a statement of the advantage and disadvantage of th ORTHO AUTOVUE innova? thanks a lot

[xbsyb]

who can make a statement of the advantage and disadvantage of th ORTHO AUTOVUE innova? thanks a lot

[cplatt36]

Question is the autovue replacing the Pro-vue?

[Rosemary]

who can make a statement of the advantage and disadvantage of th ORTHO AUTOVUE innova? thanks a lot

We've used the AutoVue since 2004, and the upgraded Innova since 2006. In Australia, the casstte columns use glass beads, not gel

As we went straight from tube to automation with the AutoVue, can only comment from this perspective-

Advantages:

*standardised test reporting

*cassette images stored and viewable on PC - Windows based

*very easy to use - training time minimal

*reaction from interference cold aggs, rouleaux almost eliminated

*increased safety to user-no glassware, sytem fully enclosed

*load and walk away - free up staff to do other tasks

*software package - Resolvigen- for antibody ID with education / info re ID'd antibody

*can interface to LIS

Disadvantages :

*Group interpretaion of AB patients recently transfused with multipe grp A red cells is poor - fwd group can appear as B: reaction flagged as forward & reverse typing mis-match - all these we resolve in tube. All our group mis-matched stem cell tx patients are grouped in tube & not on AV.

*Stat samples not truly handled as stat - AV schedules samples in batches i.e stat sample not immediately addressed once on board

*Large fluidic resevoirs not housed - stored under intrument with multiple tubing threaded through the outside of the intrument; messy looking

Hope this is useful

[Rosemary]

We've used the AutoVue since 2004, and the upgraded Innova since 2006. Disadvantages :

*Group interpretaion of AB patients recently transfused with multipe grp A red cells is poor - fwd group can appear as B: reaction flagged as forward & reverse typing mis-match - all these we resolve in tube.

Ooops, meant grouped as an A not B

[xbsyb]

hi , Rosemsry,thank you very much,

[xbsyb]

hello #2:cplatt36,yes ,it is just i want to know ,could you make a statement? thanks

[TimOz]

Hi XBSYB,

Please put your country in your profile. It makes a big difference as the analysers mentioned are not available in some regions and are known by a number of different names.

We do not use an Innova but I am very familiar with the AutoVue (earlier software) and the Innova and installed a few. This Innova instrument is Swiss and made by Tecan. The engineering is excellent and very reliable and built like a Swiss watch. The provue is a Spanish built unit (I beleive) by Grifols or a consulant engineering company and it is called the Diana or ID-WA or ID Walkaway or ID WA Compact or ID GelExpress and so on. It has been available in many variations.

The second main benefit that is not obvious is that the Innova has 2 doors compared to the Provue's one door. This means that the Provue/Diana is basically a batch analyser as once running, does not like the door being opened once running. For this reason, often 2 units are installed, one for routine samples and one for stat samples. The Innova, on the other hand, has a main door and a second sample and reagent entry door on the left that is independant of the main door that can be opened at any time. This means that the instrument can be loaded with a batch os samples and a stat can be added later at any time and the software does a pretty good job of feeding the stat test into the system as soon as possible without interrupting the routines.

The Innova has new Windows based software is very nice and allows flexibility in reagent red cell choice. The previous version had OS2Warp based software that was pretty nasty.

You need to check that the throughput and turn around time suit your needs. Some labs in Australia have a single instrument that runs well. Other labs will have 2 units to cope with workload, TAT. routine samples plus stats and allow downtime for service.

FYI, there are 2 new large throughput analysers coming from Grifols and DiaMed/BioRad but they are unlikely to be available in the US any time soon due to FDA license timing. These have not been really seen and the jury is still out but the quoted throughput is higher than current instruments.

In summary, the Innova appears to be a much better instrument for most labs than the Provue/diana instrument.

[crummer]

Disadvantages: Cold antibodies,...... auto antibodies, ........ the Rh/K cards always have a slight mixed field with K + samples.

Advantages: probably best high throughput instrument using card / casette technology