Eagle Eye Posted April 1, 2006 Share Posted April 1, 2006 Recently we encountered a patient who is C+ and patient has clear cut anti-C in plasma , AC negative & DAT negative. no transfusion as per info from the patient. ANy idea , waht is going on here? Link to comment Share on other sites More sharing options...
johna Posted September 20, 2006 Share Posted September 20, 2006 Recently we encountered a patient who is C+ and patient has clear cut anti-C in plasma , AC negative & DAT negative. no transfusion as per info from the patient. ANy idea , waht is going on here? Any possibility this might be anti-Ce? This would react not react with the patient's own cells if his genotype was DCE/dce. Link to comment Share on other sites More sharing options...
Mabel Adams Posted September 21, 2006 Share Posted September 21, 2006 Did the patient get any sort of immunoglobulin that might have contained anti-C or any donor unit that might have? Link to comment Share on other sites More sharing options...
Julie Shannon Posted September 28, 2006 Share Posted September 28, 2006 it might also be some sort of DAT neg auto antibody. You might want to try autoadsorption just to see if it might work. Link to comment Share on other sites More sharing options...
marilynm Posted September 28, 2006 Share Posted September 28, 2006 Alloanti-C in C-positive people have been reported several times in the literature. Check the Antigen Facts book of Reid and Lomas-Francis. If the person is Black, then their red cells could be C+weak and VS+, and this is the type of situation that most often occurs when there is alloanti-C in C positive people. Is the person Black? marilynm Link to comment Share on other sites More sharing options...
marilynm Posted September 28, 2006 Share Posted September 28, 2006 I forgot to ask if the patient is female and has a history of any pregnancies? We had a White pregnant female who had alloanti-C in her serum, was C-positive. There have also been examples of naturally occurring anti-C. marilynm Link to comment Share on other sites More sharing options...
Eagle Eye Posted September 28, 2006 Author Share Posted September 28, 2006 Sorry I can not get all the information as I am home with my Son. I will try to get the info next week. Link to comment Share on other sites More sharing options...
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