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Refrigerated Platelets


kimblain

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Cold-stored platelets are being used in limited situations in the US. To my knowledge, they can only be used for active bleeding, which FDA has loosely defined. Most hospitals are not yet using them because of this loose definition of "active bleeding" and reimbursement. Here are some articles:

https://www.fda.gov/media/132379/download

https://mrdc.amedd.army.mil/index.cfm/media/articles/2015/FDA_approves_cold-stored_platelets_for_resuscitation#:~:text=The agreement by the FDA,33.8 to 42.8 degrees Fahrenheit.

 

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Decades ago that's how we used to store plts.  Good for 3 days at that time.  My understanding of such is that refrigerated plts are able to function upon transfusion whereas the current room temp plts require an "adjustment" period before they are clinically functional.   I'd like to hear the current feelings on such (just so I'm not laboring under a delusion).

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