BBfuntimes Posted December 17, 2021 Share Posted December 17, 2021 In the recent months we have seen an increase in positive immediate spin crossmatches (grainy to 1+ reactions). Antibody screens are negative in gel. I am wondering if others are seeing this and if it is perhaps a COVID thing. Link to comment Share on other sites More sharing options...
David Saikin Posted December 17, 2021 Share Posted December 17, 2021 Capture technology? Link to comment Share on other sites More sharing options...
Arno Posted December 20, 2021 Share Posted December 20, 2021 Not that I am aware of. There are publications reporting an increase of DAT positive samples amongst Covid-19 patients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414594/ According to the authors, the eluate (IgG) reacts only with cells from Covid patients and this state is likely to be transient (related to hyperinflammation in these patients). Walter Isenheim, Malcolm Needs, Yanxia and 2 others 1 4 Link to comment Share on other sites More sharing options...
AMcCord Posted December 21, 2021 Share Posted December 21, 2021 We don't tend to do much Blood Bank testing for Covid patients now, however when we were doing types to give convalescent plasma we did see a few funky reactions in backtypes. Nothing strong. Whether they were Covid related or just that patient...who knows. John C. Staley 1 Link to comment Share on other sites More sharing options...
MAGNUM Posted December 22, 2021 Share Posted December 22, 2021 We use Capture, and we as well have seen an increased number of weak reaction at immediate spin. AMcCord 1 Link to comment Share on other sites More sharing options...
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