Validation of tube to gel method for isoagglutinin titers

[Transfusion98]

Just wondering if anyone would be willing to share their validation protocol?  We currently titer in tube but are moving the gel titers on the Visions.

Thanks!

 

 

[David Saikin]

I think this is something that you need to think about what you want.  You can set up the validation titers (you should document  the "how" for both tubes and gel).  It is once you get your results you will have to determine that a) you like them and b) you'll have to document how you will notify your users that you have changed.  I think that you should continue with tube titers on any patient you are currently doing titers on (don't change in the middle).  Most of your validation plan will deal with how you are running these tests; and then how you will disseminate to your users.  Not much help - most of this is dependent on your procedures.