Method to Method Comparison

[sullivanlawyer]

Hello,

Does anyone have a method to method SOP/form they would like to share for transfusion services?

 

Michele

[David Saikin]

i sent you a message w the info you requested

[sullivanlawyer]

Hi David,

I am struggling with a method to method comparison for apheresis platelet counts.  Please see below.  I wrote this for my data eval and determination of acceptance.

● An acceptable bias or allowable total error of ±7.0% for platelet count was set for this method to method comparison.  The mean of the Abbott Cell-Dyn method is 1.5408 with a standard deviation of 0.2248.  It is 95% confident that the sample mean falls between 1.47199 and 1.60961 or ±4.5%. 

The mean of the Coulter DxH 800/600 is 1.5397 with a standard deviation of 0.2376.  It is 95% confident that the sample mean falls between 1.467 and 1.612 or ±4.7%.

The difference between the two methods are within allowable error for 41 of 41 samples tested.

 

I did a method to method on EP evaluator.  Does this sound correct to you?

[sullivanlawyer]

Hi David,

you usually respond quickly. I hope you are a Covid safe. 
michele

[David Saikin]

Sounds reasonable to me.  As long as you have defined what the acceptable comparisons are I would say you are fine.