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DVI


AB123

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How common is DVI? Have done a google search but carnt find much information.

Any sites that actually dual screen neonates or adults with both DVI+ and DVI- D clones? If so how often do you identify one if ever?

Thanks

 

 

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Partial DVI is the single most common partial D found in the White populations, having a phenotype frequency of between 0.02 and 0.05% in these populations.  Have a look in Daniels G.  Human Blood Groups.  3rd edition, 2013, Wiley-Blackwell and/or Klein HG, Anstee DJ.  Mollison’s Blood Transfusion in Clinical Medicine.  12th edition, 2014, Wiley-Blackwell.  You will find several references in either or both of those books.  Alternatively, look for http://www.rhesusbase.info/ in your search engine (which is a superb site).

It is only really necessary for the "donor side" to look for individuals with Partial DVI.  There really is minimal evidence (even that is stretching it) that foetuses/babies who are Partial DVI can cause their D Negative mother to produce an anti-D, but it would be almost impossible to put that particular genie back in the bottle!  That having been said, in my experience, the moment that people find that the baby is a Partial DVI, they shoot the mother full of anti-D immunoglobulin, without ever testing the mother to find out if she is also a Partial DVI.  One day, a virus, unknown at present, will be passed on in the anti-D immunoglobulin, and it will be proved that it need not have been given in the first place, and then, all Hell will be let loose.

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