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Low vs High Triggers


SMILLER

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If you read the paper carefully, the major difference in outcomes is reoperation and other complications clearly unrelated to transfusion triggers.  Poor choice of endpoints and data analysis and totally non-credible conclusion regarding clinical outcomes in my view.  The immense body of data showing that restrictive transfusion is not only safer but likely superior tells us this is a small pilot study with little to no real meaning for clinical practice.  Cannot imagine what the reviewers were thinking when they let them publish this with these conclusions in the current form. 

Edited by Neil Blumberg
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Any study that challenges the status quo should be met with caution (but NOT with derision I think!)  This is an admittedly only a pilot study that, like others before it, suggests more robust studies need to be done.  I think it is interesting though because it is from a different standpoint -- that of a vascular specialist or a perfusionist.

Scott

Edited by SMILLER
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