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Bb_in_the_rain

Identification of Fyx Allele in Patients

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If Fyx allele is identified in donor, we consider this as Fy(b+) since it can elicit antibody product in the recipients. 

My question is- 

Are patients with Fyx allele capable of producing anti-Fyb? Are there any case reports? 

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8 hours ago, Malcolm Needs said:

I have never heard of a patient with the Fyx allele producing an anti-Fyb.  Logically, they should not be able to so do, but, if they do, it would be an auto-antibody.

That will be my assumption as well. When I read up "Olsson M, et al. The Fyx phenotype is associated with a missense mutation in the Fyb allele Preductin Arg89Cys in Duffy glycoprotein.", authors explictly did not mentioned that individuals with Fya/Fyx does not produce anti-Fyb. 

That lead me to second guess myself and look for case reports but could not find any. 

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