For those of you treating cells with DTT for patients taking daratumumab/darzalex: Have you come across a positive autocontrol, with treated and untreated cells?
Currently, patient on DARA: initial screen-panagglutinin, auto-positive.
Testing with treated cells: screen-negative, auto-positive.
QC-valid (testing Kpos and Epos cell) antigen typing for K-neg, E-pos
I have been unable to find any research with this information. We are currently in the process of validating DTT treatment.
Any advice would be welcomed.
Thank you