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Found 3 results

  1. Hi All, We are about to move from using Bio-Rad IH-1000 to Immunocor NEO in our blood bank department. As most of you are already aware, the IH-1000 uses column agglutination technology (CAT), whereas the NEO uses Solid Phase Red Cell Adherence (SPRCA) assay. SPRCA is known to be more sensitive, which is great when picking up on elusive antibodies belonging to Kidd blood group system (I think ). My concern is about the techniques which employ the use of indicator cells that are coated with anti-IgG. It will only pick up on IgG antibodies and none of the IgM antibodies. How significant is this? Is there any way of picking up IgM antibodies using such technique? Or should we not worry since IgM antibody does not usually reaction at 37C? Regards, Jermin
  2. We are considering using the edit function on Neo to manually review and interpret equivocal reactions on antibody screen tests performed on Neo. We have been getting many, many equivocals over the past several months and all instrument and reagent solutions are temporary. We are repeating a significant number of tests which is requiring extra resources of reagent and time, not to mention delay to patients. All of the antibody screen repeat test results are negative so we are looking into thoughtfully editing the Neo result. Is anyone routinely using the Edit feature and what is your algorithm for interpretation? Thanks!
  3. Hi I am reference coordinator at 450 bed Level 1 Trauma Center. The last few months I have seen a few times when all three Neo screening cells are about 2-4+ pos and then Neo panel was all negative. These patients did not have Rhogam and tested negative in PEG testing. I have also seen this happen with several different Neo screening cells lots. One patient screen on Lot R369 was 3+ pos for all three cell on both Neo instrument but had a negative Neo panel on Lot ID201. Then this patient was tested against another screening Lot (R374). Which resulted in 3+ reactions on all three cell on one instrument but the screen was negative on the other instrument. 30 min Peg screen and auto control was negative. Immucor is reviewing this one but has not responded yet. Another patient example is a patient screen on Lot R384 tested 3+ on cell 1, 2+ on cell 2, and ? on cell 3. Since the other Neo was down the Tech repeated the screen with Manual Solid phase and all 3 screening cells were 3+ pos. The Neo Panel DN072 was all negative and so was PEG screen and panel. Has any one else had a solid phase panagglutinin positive screen and corresponding neg solid phase panel?
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