This is a question posed by my Laboratory director: Given this scenario, "Patient with a history of anti-Jka whose current antibody screen is negative. Two units of RBCs are ordered for transfusion tomorrow evening." 1. Does your blood bank crossmatch random donor units and issue crossmatch-compatible donor units? or 2. Crossmatch Jka- donor units and issue crossmatch-compatible Jka- donor units? or 3. Do you think this is a trick question? I'd appreciate as many responses as possible. Thanks, Dan