From my manager's "old school" approach that if a clinically significant antibody is present with a warm auto, it will react alone without enhancement media due to its supposed "high" titer. Similar to slsmith, we incorporate this approach when we have panagglutination in our more sensitive methodologies and are trying to "look through" these reactions. It's never our sole method or what we use to report, but just another arrow in the quiver of techniques.