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24hrs from time of thawing...

Thanks for your reply! All will be considered and looked into further....... Interesting enough, my ARC supplier sent me some additional information regarding the Cryoprecipitated AHF Pools including the brochure posted. There is a difference in expiration time as it has 6hrs instead of 4hrs on the brochures sent to me from the ARC Distribution Dept. Again further investigation will be done as you have made very good points.

I too consulted with our ARC supplier. See statement below: I met with our Medical Director, as well as consulted with ARC and AABB materials and here is your official answer and it is best described in the 2010 edition of the "Compendium of Transfusion Practice Guidelines" on p.52.... "If pooled cryo is from a closed single unit or has been pooled using an FDA-approved sterile connecting device, it should be transfused within six hours of thawing. If it is an open system or if units have been pooled after thawing by entering the containers, it should be transfused within four hours." The pooled cryo that we (ARC) manufacture is in a closed system and is obviously frozen upon arrival as five single units into one bag so upon thawing in your water bath you have six hours of shelf life to transfuse.

Yes, in reviewing the technical manual, there is a conflict between the two......

According to the ARC Transfusion Practice Guidelines, if it the thawed pooled cryo is from a single unit ( which is what we have, the Cryo pool of 5) or units pooled using a sterile docking (FDA approved), it can be transfused within 6 hours of thawing. (Closed system)

Hello to All, My lab currently uses the ARC pooled cryo of 5. We dispense these products in a closed system so it has a 6hr expiration. What is your policy if the product is returned to the lab greater than 30min but within the 6hrs at room temp?