Currently we have random donor platelets that we may pool into a single product. These random platelets are bacterial tested by our current blood supplier. We use 6 random donor platelets to equal a single apheresis product, but I've seen 4 randoms used at times to match an apheresis product. This pooled product is used when apheresis product inventory is low, or when there is a suspicion of platelet refractoriness. We usually see patients who do not display a "bump" with an apheresis product. We will switch to a pooled product to see if we see a "bump". If yes, we send specimen for platelet antibody screen testing. If positive, we request a crossmatch compatible platelet product for patient.