That makes sense to me as well, although we would rather save the patient (or hospital) money that would be spent on a reference workup and just do a gel crossmatch. So I may make an M37 that's significant.
After skimming through the entire The Blood Group Antigen FactsBook for transfusion reactions and HDFN, it is my decision that according to that book A1, DRHIG, Lea, Leb, Lua, M, N, Wrb, XGA and Yka are clinically insignificant, as well as cold auto, and warm auto without specificity once underlying allo-antibodies are ruled out and a negative screen. Does that sound right? We have a current warm auto patient in house with no underlying allo-antibodies and they recommend transfusion with E-, c-, K-,Fyb- and Jka- red cells. Yikes! I should just order antigen negative units from the blood center, because otherwise I would have to screen 159 units to find 1 negative! Maybe she will move out of state when she has recovered!