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R1R2

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  1. Like
    R1R2 reacted to Malcolm Needs in Explanation for positive DAT and Elution results?   
    Ah, then I think there is your answer.
     
    IVIG is a sort of soup, with all sorts of antibodies in it, including anti-A, anti-B and anti-AB.  In one case in the UK, at one stage, when these antibodies could be present in quite high titres, this was the cause of prolonged red cell apalasia in an ABO mismatched stem cell recipient.  Within the UK, these "allowable" titres have now been reduced, but the antibodies are still there in small amounts.
     
    Elution can be a very sensitive technique (adsorption and elution is used, for example to tell the difference between someone who genuinely lacks a high incidence antigen, such as Lan, and those that express the antigen extremely weakly; too weakly to detect by normal serological techniques) and so any anti-A, anti-B and/or anti-A,B in the IVIG is likely to sensitise your patient's red cells and you would be able to elute them back off.
     
    In a way, it is the same as the prophylactic anti-D immunoglobulin that is given antenatally that can sensitise a D+ baby's red cells, but is too weak to cause HDFN.
     
    I would be extremely hesitant to "diagnose" a haemolytic anaemia from your evidence bloodbankninja.  At best, from your evidence, you have a case of a serological transfusion reaction, unless the child requires a transfusion, and, even then, the requirement for a transfusion may be coincidental, due to the underlying pathology.
     
    Good call R1R2.
  2. Like
    R1R2 got a reaction from Yanxia in Explanation for positive DAT and Elution results?   
    Has this patient received IVIG or something similar?
  3. Like
    R1R2 got a reaction from Malcolm Needs in Explanation for positive DAT and Elution results?   
    Has this patient received IVIG or something similar?
  4. Like
    R1R2 reacted to ksmith in In need of a new room temperature monitoring device   
    The checklist item is COM.30350 Reagent Storage - All reagents....stored as recommeded by the manufacturer.  Under the Note it states "If ambient storage temperature is indicated, there must be documentation that the defined ambient temperature is maintained.....
  5. Like
    R1R2 reacted to tbostock in Accepting RH type results on OB patients from other facilities   
    Nope.  We had a few discrepancies with prenatal blood types from other labs.  Weirdly, they were all AB Neg.  Found out the doctor's office staff manually types in all blood types to the prenatal chart report.
     
    You guessed it....the lab reports all said "Ab screen Neg"...the secretary thought that meant AB Neg.  You really can't make this stuff up.
  6. Like
    R1R2 reacted to tbostock in Blood Bank ID Bands   
    We got rid of our bands last year.  Best thing we ever did.
  7. Like
    R1R2 reacted to Rh-fan in Expired ABID Panels   
    Mabel you have a point but still my mind goes in the direction of goodchild.
    It is not possible to test every day, every antigen on every cell you use.
    But we can follow the directions of the company selling the panel. If the campany can sell a panel that can be used for 2 months it is a big positive selling point (compaired to the other company's). They do not stretsch the time you can use the panel because they can not clame the antigen prsentation is good enough. Why is almost everbody that uses a panel then stretching that time, do they know better than the company (even without proper controls)?
    Is anyone using reagents for Hb or any other test, that is expired? Then why do we do it for ABID panels. I do no see the difference.
    Peter
  8. Like
    R1R2 reacted to estiner in Accepting RH type results on OB patients from other facilities   
    We accept a copy of the lab results from a state certified laboratory for the 28wk dose. Interestingly we only get the Rh negatives and would not see the weak D's if reported as Rh positive. Giving Rhogam to a weak D patient is the decision of the attending physician. We recommend giving it to weak D patients but not all our physicians agree. If there is no certified report we perform the T&S prior to giving the Rhogam. Since we do not perform weak D testing on adults, those patients would be reported as Rh negative. Upon admission for delivery, Rh negative moms only have a standard T&S ordered.
  9. Like
    R1R2 reacted to Deny Morlino in Rbc Returned Unused By Nursing   
    This is the interpretation here as well.
  10. Like
    R1R2 got a reaction from DAWNA1983 in units spiked not transfused returned to the blood bank   
    We do not accept a unit back if it was spiked. I encourage the RN to try to complete the transfusion within 4 hours of entry or discard the unit. I will update the BB records if unit was not transfused and discarded in the patient care area.
  11. Like
    R1R2 got a reaction from AMcCord in Saline incubation...why is this SOP still allowed?   
    We are a CAP accredited lab and 2x year we compare all our testing methods. We compare gel, LISS, PEG, saline techniques. All methods have detected all clinically significant antibodies.
    R1R2
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