I remember seeing a blurb about QCing each methodoly in use but can't find it in CAP. It might have been somewhere else. But CAP does say that QC is required for only 1 vial reagent/lot in use
TRM.31400 Antisera/Reagent Red Cell QC Phase II
There are records of acceptable reactivity and specificity of typing sera and reagent
cells on each day of use, including a check against known positive and negative cells or
antisera, or manufacturer's instructions for daily quality control are followed.
NOTE: Unless manufacturer's instructions state otherwise, the following apply:
■ Each cell used for antibody detection must be checked each day of use for reactivity of at
least one antigen using antisera of 1+ or greater avidity.
■ Typing reagents such as anti-D, anti-K, anti-Fy(a), etc. must be checked each day of
use.
■ Anti-IgG reactivity of antiglobulin reagents may be checked during antibody screening
and crossmatching.
■ Typing sera and reagent cells must be checked for reactivity and specificity on each day
of use, including a check against known positive and negative cells or antisera.
This checklist requirement can be satisfied by testing one vial of each reagent lot each day of
testing.