As stated above, currently, the only source of an X-ray radiation source, blood irradiator in North America is Best Theratronics, Canada. This system is currently designated Raycell. This system was initially designed, manufactured and commercially offered to blood processing laboratories in the U.S. in the 1998-1999 time frame. It was designated as the RS 3000. In 2003, this system was licensed to MDS Nordion at which time it was designated the Raycell by Nordion. In latter 2007, MDS Nordion sold its entire irradiation product line (radioactive sources Cs-137 and Co-60), icluding Raycell, to Best Medical. Other than blood bag canister volume and the addition of an energy reflecting liner? In the canister, Raycell’s design has not changed since the initial design. It lacks a number of features important for current blood irradiation procedure. There is rumoured pricing over the past several years ranging from $146,000. to $250,000. USD with rumoured annual maintance agreements costs ranging from $10,000. to $22,000. USD. The major problem with all X-ray radiation source, blood irradiation equipment, available in North America and in Italy and Japan, lies in the use of X-ray sources (tubes) designed for imaging and not as radiation sources. The basic technology has not changed over the past 100 years. Over time the technology used in these tubes results in non-reliability of the X-ray tubes. Unfortunately, blood processing laboratories have born the brunt of the problem as reflected in the high initial cost of the systems and high maintenance costs. The exorbitant initial cost of the equipment is a result of large company overhead and no competition. The high maintenance cost reflects the use of commercially available, industrial imaging X-ray tubes and their replacement. The exorbitant pricing makes it very difficult for the small to medium size blood processing laboratory to both cost justify the initial cost of the equipment and its on-going maintenance cost. The Irradiation Machines advertisement below your post lists irradiation equipment designed for research and other applications; not for blood irradiation. As such it has no FDA clearance for blood irradiation.