mjohnred

I just answered this question. My Score PASS

Currently our procedure for Cold Agglutinins is to put CBC tube in 37 degree heat block for 15 minutes and if that doesn't work to extend time for 15 more minutes. However there are times when this will not work if the titer is high on the Cold Agglutinin. I'm trying to find out what other facilities do in this situation. We have tried doing warm saline replacement, but currently our procedure for a saline replacement states that RBC count before replacement should match the RBC count after the replacement within 5%. This rule will not work with a Cold Agglutinin, so if you do a warm saline replacement how do you confirm you are putting out accurate results. Also what results do you report from the replacement? I'm trying to standardize our practice so everyone is on the same page. Your input is greatly appreciated and if you can share a procedure that would be great too. Thanks for your help