Before we send out any workups to a reference lab we first run a gel panel. If the auto control is negative and all allo-antibodies are ruled out, with one or more positive cells, we will call it a non specific antibody, so full crossmatching is done, a patient safety issue. I know gel has been an issue with, a lot of non specific reactions, but keep in mind gel is much more sensitive than tube method so you cannot just dismiss a positive gel result by getting a negative tube result. Then there are patients in which everything is positive in gel so we tag them to use tube method only, this may be due to an antibody to the gel itself. We do alot of workups. Cold antibodies do get detected in gel. If we do get Mixed field reactions we convert to tube method to rule out colds and rouleaux. If we get a positive auto control in gel, we repeat it by tube method and if still positive in tube we then send it out to a reference lab for warm auto antibody workup. These are just a few things we do. I have a whole SOP just dedicated to working ABI in gel. Even though it may be some cost we do keep 3% screen cells and 1 3% panel on hand. This has saved us the more costly sendouts to a ref lab.