So for example the question below
If you only knew that the patient had been transfused but no other details how would you phenotype or would you just obtain a genotype?
The BSH guidelines say " If the patient is known to have been transfused in the previous three months, phenotyping may be misleading"
Most regularly transfused patients such as Haemoglobinopathy patients admittedly would already be phenotyped but if they were not they would required Rh K matching units, DARA patients would you Rh phenotype if units are required ASAP but you have time for a crossmatch.
What further tests would you do if you had the resources to ensure you provided matched units
So for example after the elution to identify the antibodies can you use the RBC left from the process to phenotype ? or does the elution damaged the RBC is there another procedure for phenotyping if the patient has been recently transfused?
Misleading means ? - What anomalies would you actually see ? weakened reactions, dual populations (if ABO) anything else?
Why with warm autoantibodies does elution not help ? What about in pregnancy are there any anomalies with elution/adsorption/phenotyping ?
Thanks