We antigen match our sickle cell patients who are on chronic transfusion therapy for the five major Rh antigens, Kell, Fya, and Jkb. At least that is what we started with; it has grown from there. One of the issues we see in our area is that most of the units are from white donors.
Most if not all of the new patients are typed and matched for V/VS and Jsa. These antigens are rare to non-existent in whites, but are found in a sizable percentage of blacks. So when you target black donors to be able to match the Duffy and Kidd antigens, you may be setting your patients up to make anti-V/VS and or anti-Jsa.