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  1. If we have a patient w no detectable ABO isoagglutinins our procedure is to perform an ahgxm in addition to the immediate spin. When I was validating gel we had a few patients w no detectable ABO abs: they weren't detectable at ahg either.
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  2. I am a little worried about this because, even if there are VERY low numbers of isoagglutinins, if there is a normal level of complement, it can still be extremely dangerous, as there is massive amplification within the complement system (see the excellent attached PowerPoint lecture, written for me by my friend Grant Webb). The Complement System.pptx
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  3. A lecturer I listened to discussed MTP and stated that using Rh positive packed cells keeps the patient alive. He said that if anti-D is built, it can be dealt with when the woman gets pregnant. If she dies because she didn't get transfused with Rh positive packed cells, she certainly won't even have the opportunity to become pregnant. So, there's that.
    1 point
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