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Showing content with the highest reputation on 06/27/2020 in all areas

  1. Can I just point out here that no one serological test, or even combination of tests will detect all weak / variant Ds . And that includes women who test D+ but actually have a partial D and may make anti-D antibodies. It is SO important to know your reagents, and know what your anti-D reagents will and will not detect
    2 points
  2. First of all, please do not worry. IF you do have anti-D antibodies, and they are real antibodies, this is only one of a number of tests that the doctors will do during your pregnancy to make sure everything is going OK with your baby. What they should do is recheck your blood for anti-D levels now and again in about 4 weeks' time to see if there is any change. It will show anti-D because of the Rhogam, but the important thing is to see whether the level increases significantly over time. Also, even now, if it is very high (VERY unlikely) then that would indicate it's real anti-D as opposed to the Rhogam. Ultrasound is a good idea. It is usually done anyway during pregnancy, but it will also show if something is happening that they need to react to.
    1 point
  3. True Joanne, it is very fast, but one of my points about this is that, when a baby is found to have a Weak or Partial D (such as Partial DVI), it would be good practice to test the mother for Weak or Partial D expression, if this has not already been done, because she may be the source of the mutant gene leading to the baby's Weak or Partial D type. If she is the source, then it is a moot point, to say the least, as to whether she should or should not be exposed to a human-derived blood product that may, for all we know, be harbouring novel virus that may be transfusion-transmitted. AT the very least, she should have the risk, albeit very low, explained to her before she is given the anti-D immunoglobulin.
    1 point
  4. It is not the gel test that does not detect Partial DVI, it is the monoclonal anti-D blend in the gel that you use that does not detect those four Partial DVI types.
    1 point
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