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If you're talking about resolving an ABO with the presence of a cold, I've seen using warmed cells/plasma, adsorbed plasma, or cord cells. Did they use the anti-IgG for the workup, and not the discrepancy?

I have a Helmer DH4 that is quite elderly. It's been very reliable. Thaws quickly.

I don't know for certain, but I bet they did a bit more than that. Almost all "cold" auto-antibodies are IgM, it is true, BUT, because these antibodies almost always have a very wide thermal amplitude, they would cause "spontaneous agglutination" in tests incubated at 37oC too. What they probably did was to either adsorb out the "cold" auto-antibody with something like rabbit erythrocyte stroma, or denaturation of the IgM molecules by a reducing agent, such as dithiothreitol (DTT), and only then performing tests using a monospecific anti-IgG reagent. I am quite happy to be corrected.

We have had a Helmer 4 well for years. We ONLY use bottled water (distilled/deionized) and change the water every month (unless there is a messy spill). We use the Helmer Cleanbath product (per instructions) after cleaning the unit and putting in the fresh bottled water. We use the specific bags sold by Helmer for their machine - sort of expensive, but I do not see how anything else would work right. Units thaw in 14-18 minutes and we recently used it to thaw 16 units for plasma exchange and were finished with the thawing within 1 hour. Easy to maintain and keep operating - very stable.

I believe their instructions say to change the water and clean the unit weekly.