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Worthless.

Sorry about the incomplete references. Here are the full references for the two missing :). ABO identical and washed blood transfusions as candidate strategies to reduce early mortality in acute promyelocytic leukemia. Sahai T, Henrichs K, Refaai M, Heal JM, Kirkley SA, Schmidt AE, Mendler JH, Masel D, Liesveld J, Aquina C, Blumberg N. Leuk Res. 2017 Nov;62:1-3. doi: 10.1016/j.leukres.2017.09.011. ABO-immune complex formation and impact on platelet function, red cell structural integrity and haemostasis: an in vitro model of ABO non-identical transfusion. Zaffuto BJ, Conley GW, Connolly GC, Henrichs KF, Francis CW, Heal JM, Blumberg N, Refaai MA. Vox Sang. 2016 Apr;110(3):219-26. doi: 10.1111/vox.12354.

We haven't used "Post-Storage Leukoreduction" (aka Bedside Leukoreduction Filters) for many years. Search the literature and you will find that they are essentially useless. Leukoreduction is accomplished by adhesion, not size so effective reduction is dependent upon the activity of the leukocytes. Once they 'die' and breakdown during storage (a few days), they won't adhere to the filter no matter how old the unit is. In addition, the by-products of their breakdown, which cause reactions, are now released into the plasma and there are now leukocyte fragments floating in the plasma which could result in reactions caused by pulmonary filtration of these particulates or sensitization to their HLA Antigens. Bottom Line: Leukocyte reduction is effective when performed shortly after donation while the leukocytes are still viable and will adhere to the filter.

Transfusion of ABO-mismatched platelets leads to early platelet refractoriness. Carr R, Hutton JL, Jenkins JA, Lucas GF, Amphlett NW. Br J Haematol. 1990 Jul;75(3):408-13. The role of ABO matching in platelet transfusion. Heal JM, Rowe JM, McMican A, Masel D, Finke C, Blumberg N. Eur J Haematol. 1993 Feb;50(2):110-7. ABO and platelet transfusion revisited. Heal JM, Rowe JM, Blumberg N. Ann Hematol. 1993 Jun;66(6):309-14. Association of ABO-mismatched platelet transfusions with morbidity and mortality in cardiac surgery. Blumberg N, Heal JM, Hicks GL Jr, Risher WH. Transfusion. 2001 Jun;41(6):790-3. ABO identical and washed blood transfusions as candidate strategies to reduce early mortality in acute promyelocytic leukemia. Sahai T, Henrichs K, Refaai M, Heal JM, Kirkley SA, Schmidt AE, Mendler JH, Masel D, Liesveld J, Aquina C, Blumberg N. ABO-immune complex formation and impact on platelet function, red cell structural integrity and haemostasis: an in vitro model of ABO non-identical transfusion. Zaffuto BJ, Conley GW, Connolly GC, Henrichs KF, Francis CW, Heal JM, Blumberg N, Refaai MA. An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients. Refaai MA, Fialkow LB, Heal JM, Henrichs KF, Spinelli SL, Phipps RP, Masel E, Smith BH, Corsetti JP, Francis CW, Bankey PE, Blumberg N. Vox Sang. 2011 Jul;101(1):55-60. doi: 10.1111/j.1423-0410.2010.01464.x. Providing ABO-identical platelets and cryoprecipitate to (almost) all patients: approach, logistics, and associated decreases in transfusion reaction and red blood cell alloimmunization incidence. Henrichs KF, Howk N, Masel DS, Thayer M, Refaai MA, Kirkley SA, Heal JM, Blumberg N. Transfusion. 2012 Mar;52(3):635-40. Is It Time to Reconsider the Concepts of "Universal Donor" and "ABO Compatible" Transfusions? Refaai MA, Cahill C, Masel D, Schmidt AE, Heal JM, Kirkley SA, Blumberg N. Anesth Analg. 2018 Jun;126(6):2135-2138.

AABB recommends that so you don’t have to rewrite the references on every policy when they are updated. Like above, you can have a cover sheet with current edition info. Also, when AABB issues a new edition of standards, they publish a document detailing the changes. Before the new Standards implementation date, I would go through that and document on all the changes any policy affected, action required, and date completed. I had the Medical Director sign off on that when done. Most were “not applicable”, as we were not a donor center, or “no change required to policy XYZ”.