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Showing content with the highest reputation on 08/19/2016 in all areas

  1. In the MHRA inspection I had when I was BBSup I challenged on 4 different non-conformances and had them wiped off. My current employer (and others too) seem to think that you cannot challenge their interpretation of your policies - and sometimes the interpretations are incorrect.
    1 point
  2. ISO inspectors have said the fridges have to be under direct control of the lab - a few labs I know have been told to remove their remote fridges.
    1 point
  3. noelrbrown

    Anti-CD47

    Unfortunately the answer is, it depends... If the anti CD47 is a human antibody, then it will cause a positive DAT as CD47 is expressed on most cells in the body including erythrocytes. If the anti CD47 is mouse or goat then it will not as this antibody will bind to CD47 but will not cause the same interference we see with Daratumamab. I believe recent therapies involve blocking some of the CD47 receptors.
    1 point
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